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Weight Loss Studies for People with Type 2 Diabetes

We are coordinating clinical trials for people with a wide range of health conditions. If you're on this page, we likely have an option for you.

Please review the options in our menu below, and fill out the form to speak with us or call us at (615) 329-2222.

Our team will need to speak with you to determine your interest and if you will qualify for participation.

Study medicine is provided at no cost for participants, and compensation between $1,225 - $3,000 is included for study participants as well.

For more information, please scroll past the form to read more about our studies.

Please Enter Your Details Below

Our team will contact you to help plan your initial visit and determine the right trial for you.

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Do you have Type 2 Diabetes?(Required)
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Study Details

About 38 million Americans (1 in 10) have diabetes, and about 90-95% of those have Type II Diabetes according to the CDC.  It is estimated that more than two-thirds of US adults are overweight or have obesity.  Both are significant health issues which affect millions. Are you among those who struggle with weight and glucose control?  This research study might be of benefit to you.

The FDA approved the study drug in May 2022 under the indication of improving glucose control in conjunction with diet and exercise for adults with Type II Diabetes. In November 2023, the study drug was approved by the FDA for chronic weight management for overweight adults and adults with obesity, who also have one weight-related condition, in combination with a reduced calorie diet and increase physical activity.

Currently there are no data for dosing of the study drug at higher doses than 15 mg in comparison to a placebo. 

The purpose of this trial is to evaluate the safety and effectiveness of the study drug at higher doses as compared to a placebo (6:1).  Participants will have frequent exercise and dietary counseling at their appointments.

Weight loss and glucose control are often struggles for people who have Type 2 Diabetes.

Weight loss and diet can be the first treatment recommendation, or what people try to do before seeking help. Many times this is not successful.

If this sounds like you and you are not on any medicine for diabetes, then this may be an opportunity for you.

We are seeking volunteers to participate in a study to evaluate the safety and effectiveness of a once weekly injectable research medication compared to a placebo on weight loss and glucose.  The study will last approximately 44 weeks with 15 visits to our office.  

What does the study require?

  1. High motivation to achieve weight loss and improve glucose control
  2. Commitment to attend required visits
  3. Weekly self-injections
  4. Multiple blood draws
  5. Keeping an ediary

Who can participate?

  1. 18 years of age or older
  2. NOT taking diabetes or weight loss medications
  3. Stable weight for past 3 months
  4. General good health

How to learn more?

Fill out the form below or call our office at (615) 329-2222.

Our team will need to speak with you to determine if you are interested and quality for participation.

There’s no obligation and no insurance required. All study related diagnostic tests and study medication are at no cost. 

Compensation of $3,000 may be available for participants.

If you want to help the development of future type 2 diabetes treatment, then the REIMAGINE 3 clinical research study may be for you.

What does this study require?

  1. Study commitment of up to 50 weeks with up to 11 office visits and 33 phone visits
  2. Injection of investigational study medicine with an easy-to-use injection pen once a week
  3. Multiple blood draws
  4. Daily finger sticks to check blood glucose
  5. Maintain a dosing diary and complete questionnaires using a study app

Who can participate?

  1. Must be 18 and older with a diagnosis of type 2 diabetes for more than 180 days
  2. Taking a once daily insulin injection for at least 90 days
  3. BMI ≥ 25 kg/mwith a HbA1c 7.0-10.5 %

How to learn more

You may call our office at 615-329-2222 and speak with our team or fill out our form below.  Our team will need to speak with you to determine if you are interested and qualify for participation in this research study.  All study related diagnostic tests and study medication are at no cost.  Compensation may be provided for time and travel. 

Compensation of $2,950 may be available for participants in this study. 

Do you have type 2 diabetes? 

Are you taking metformin with or without a SGLT2 medication (Invokana, Farxiga, Jardiance, Steglatro, Brenzavvy)? 

You could consider participating in this open label study evaluating the effectiveness of two injectable research medications in terms of glucose control and weight loss.  There are no placebos in this trial. 

What does this study require?

  1. Study commitment of up to 77 weeks with 15 office visits and at least 6 phone calls.
  2. Injection of investigational study medicine with an easy-to-use injection pen once a week
  3. Multiple blood draws and finger sticks (glucose meter and supplies provided)
  4. Maintain a dosing diary and complete questionnaires using a study app

Who can participate?

  1. Must be 18 and older with a diagnosis of type 2 diabetes for more than 6 months
  2. Taking metformin alone or in combination with a SGLT2 inhibitor (Invokana, Farxiga, Jardiance, Steglatro, Brenzavvy)
  3. BMI > 30 with a HbA1c 7.0- 10.5%

Interested in learning more?

You may call our office at 615-329-2222 and speak with our team or fill out our form below.  Our team will need to speak with you to determine if you are interested and qualify for participation in this research study.  All diagnostic tests and study medication are at no cost. 

Compensation of $2,150 may be available for participants in this study. 

If you want to help the development of future Type 2 Diabetes treatment, then the REIMAGINE 2 clinical research study may be for you.

You may be eligible to participate in this clinical study if you fulfil the following:

  • 18 years or older
  • Have had type 2 diabetes for more than 180 days (6 months)
  • Have a BMI ≥ 25 kg/m2

What do you need to do?

  • Inject the study medicine with an easy-to-use injection pen once a week
  • Attend regular study-related health checks and medical tests including having blood samples taken
  • Maintain a dosing diary and complete questionnaires using a study app
  • Keep in contact with the study staff during the study at regularly scheduled visits for a duration of one and a half year.

Interested in Learning More?

You may call our office at 615-329-2222 and speak with our team or complete the form below. Our team will need to speak with you to determine your interest and if you may qualify for participation in the study.  All study related diagnostic tests and the study medication are at no cost. 

Compensation of $1,225 may be available for study participants. 

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