Non-Erosive Gastroesophageal Reflux Disease (NERD)
NERD is a common condition that develops when the contents of the stomach flow back into the esophagus causing troublesome heartburn. Over time irritation and inflammation from the acid can injure the esophagus. A diagnostic endoscopic examination can determine if there has been injury to the esophagus.
Despite the availability of prescription and over-the-counter medications, the management of heartburn can be a problem. About 40% of heartburn suffers report continued symptoms after treatment.
The purpose of this study is to determine the safety and efficacy of a research medication compared to a placebo. The research medication is approved in other countries but not FDA approved in the United States. Each participant will undergo an endoscopic exam (EDG) and will participate in two phases of study. All participants will receive 4 weeks of active treatment or placebo followed by an extension period of 20 weeks of active research medication.
What does this study involve?
All participants will read and sign an inform Consent Form (ICF) and keep an electronic diary to record episodes of heartburn. If you qualify for the study, you will undergo a screening EGD. If there are no injury to your esophagus (Erosions) or other abnormalities, you will be provided with study medication and continue keeping a diary. There are 9 visits to our office over approximately 28 weeks. Study medication, laboratory, diagnostic testing and other study related procedures are at no charge.
Compensation is up to $1100.
*18 years of age or older
*Must be willing to undergo an Endoscopic exam
*Basically healthy with no active ulcers or GI bleeding in prior 30 days
*Not planning a hospitalization/surgical procedure
For more information and to see if may be eligible to participate, call 615-329-2222 or fill out our form below.